Compile Data Set for Download or QSAR

Found 319 hits of ec50 data for polymerid = 50000519,50007584   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50541849 (GS-5806 | Presatovir) Show SMILES Cc1cn2nc(cc2nc1N1CC[C@H](N)C1)[C@@H]1CCCCN1C(=O)c1cc(Cl)ccc1NS(C)(=O)=O |r| Show InChI InChI=1S/C24H30ClN7O3S/c1-15-13-32-22(27-23(15)30-10-8-17(26)14-30)12-20(28-32)21-5-3-4-9-31(21)24(33)18-11-16(25)6-7-19(18)29-36(2,34)35/h6-7,11-13,17,21,29H,3-5,8-10,14,26H2,1-2H3/t17-,21-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Human respiratory syncytial virus A2 Fusion protein expressed in Hep2 cells assessed as reduction in virus-induced cytopathic effect af...				ACS Med Chem Lett 11: 1145-1151 (2020) Article DOI: 10.1021/acsmedchemlett.0c00008 BindingDB Entry DOI: 10.7270/Q2GB27NK
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542668 (CHEMBL4645289) Show SMILES COc1ccc(cc1OC)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C27H24ClN5O3/c1-35-25-8-6-20(15-26(25)36-2)33-23-9-11-30-16-24(23)32(27(33)34)17-21-14-18-13-19(28)5-7-22(18)31(21)12-4-3-10-29/h5-9,11,13-16H,3-4,12,17H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50450579 (JNJ 2408068 | JNJ-240806 | JNJ-2408068 | R-170591) Show SMILES Cc1ccc(O)c(Cn2c(NC3CCN(CCN)CC3)nc3c(C)cccc23)n1 Show InChI InChI=1S/C22H30N6O/c1-15-4-3-5-19-21(15)26-22(25-17-8-11-27(12-9-17)13-10-23)28(19)14-18-20(29)7-6-16(2)24-18/h3-7,17,29H,8-14,23H2,1-2H3,(H,25,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	0.160	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of RSV Long fusion protein assessed as decrease in virus induced syncytium formation in infected human HeLa/M cells				J Med Chem 61: 10228-10241 (2018) Article DOI: 10.1021/acs.jmedchem.8b01394 BindingDB Entry DOI: 10.7270/Q2445Q18
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542663 (CHEMBL4647497) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C26H22ClN5O3S/c1-36(34,35)22-7-5-20(6-8-22)32-24-10-12-29-16-25(24)31(26(32)33)17-21-15-18-14-19(27)4-9-23(18)30(21)13-3-2-11-28/h4-10,12,14-16H,2-3,13,17H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542624 (CHEMBL4639647) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C22H23ClN4O3S/c1-31(29,30)10-2-9-25-18(12-15-11-16(23)3-6-19(15)25)14-26-21-13-24-8-7-20(21)27(22(26)28)17-4-5-17/h3,6-8,11-13,17H,2,4-5,9-10,14H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542631 (CHEMBL4633144) Show SMILES Clc1ccc2n(CCCC#N)c(Cn3c4cnccc4n(C4CC4)c3=O)cc2c1 Show InChI InChI=1S/C22H20ClN5O/c23-16-3-6-19-15(11-16)12-18(26(19)10-2-1-8-24)14-27-21-13-25-9-7-20(21)28(22(27)29)17-4-5-17/h3,6-7,9,11-13,17H,1-2,4-5,10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542633 (CHEMBL4642009) Show SMILES FC(F)(F)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C22H20ClF3N4O/c23-15-2-5-18-14(10-15)11-17(28(18)9-1-7-22(24,25)26)13-29-20-12-27-8-6-19(20)30(21(29)31)16-3-4-16/h2,5-6,8,10-12,16H,1,3-4,7,9,13H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.251	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542667 (CHEMBL4635306) Show SMILES COc1ccc(cc1C)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C27H24ClN5O2/c1-18-13-21(6-8-26(18)35-2)33-24-9-11-30-16-25(24)32(27(33)34)17-22-15-19-14-20(28)5-7-23(19)31(22)12-4-3-10-29/h5-9,11,13-16H,3-4,12,17H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.251	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542648 (CHEMBL4644121) Show SMILES CC(C)CCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12 Show InChI InChI=1S/C22H25N5O/c1-15(2)7-10-25-18(11-16-12-23-8-5-19(16)25)14-26-21-13-24-9-6-20(21)27(22(26)28)17-3-4-17/h5-6,8-9,11-13,15,17H,3-4,7,10,14H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.251	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542647 (CHEMBL4644338) Show SMILES FC(F)(F)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12 Show InChI InChI=1S/C21H20F3N5O/c22-21(23,24)6-1-9-27-16(10-14-11-25-7-4-17(14)27)13-28-19-12-26-8-5-18(19)29(20(28)30)15-2-3-15/h4-5,7-8,10-12,15H,1-3,6,9,13H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.251	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554856 (CHEMBL4740044) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(Cl)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)[C@H]1C[C@H](O)C1 |r,wU:34.38,wD:1.0,36.41,(13.73,-43.38,;14.51,-42.05,;15.29,-43.38,;16.82,-43.38,;17.59,-42.04,;16.81,-40.71,;15.27,-40.71,;14.49,-39.38,;12.95,-39.39,;15.26,-38.04,;16.8,-38.04,;17.56,-36.7,;19.1,-36.7,;16.78,-35.37,;15.24,-35.38,;14.48,-36.72,;12.94,-36.73,;11.74,-37.51,;11.5,-35.99,;12.71,-35.03,;10.22,-35.65,;9.47,-37.05,;10.34,-38.05,;9.27,-38.98,;7.94,-38.21,;9.27,-40.52,;7.94,-41.3,;7.94,-42.84,;9.27,-43.6,;10.61,-42.84,;12.08,-43.31,;12.98,-42.06,;12.06,-40.81,;10.6,-41.3,;6.61,-43.61,;6.21,-45.1,;4.73,-44.71,;3.39,-45.48,;5.12,-43.22,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.270	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542675 (CHEMBL4644767) Show SMILES Fc1cnccc1-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O |(29.27,-3.65,;27.77,-3.33,;27.29,-1.86,;25.79,-1.54,;24.75,-2.69,;25.23,-4.15,;26.73,-4.47,;27.21,-5.93,;28.67,-6.41,;30,-5.63,;31.34,-6.4,;31.34,-7.95,;30.01,-8.72,;28.67,-7.95,;27.21,-8.43,;26.73,-9.89,;25.22,-10.21,;24.08,-9.17,;22.75,-9.94,;21.29,-9.47,;20.14,-10.49,;18.68,-10.02,;20.47,-12,;21.92,-12.47,;23.06,-11.45,;24.59,-11.61,;25.36,-12.95,;26.9,-12.95,;27.67,-14.28,;29.21,-14.29,;30.75,-14.28,;26.3,-7.18,;24.76,-7.18,)| Show InChI InChI=1S/C24H18ClFN6O/c25-17-3-4-20-16(11-17)12-18(30(20)10-2-1-7-27)15-31-23-14-29-9-6-22(23)32(24(31)33)21-5-8-28-13-19(21)26/h3-6,8-9,11-14H,1-2,10,15H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.316	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542665 (CHEMBL4639685) Show SMILES COc1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C26H22ClN5O2/c1-34-22-7-5-20(6-8-22)32-24-10-12-29-16-25(24)31(26(32)33)17-21-15-18-14-19(27)4-9-23(18)30(21)13-3-2-11-28/h4-10,12,14-16H,2-3,13,17H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.316	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554858 (CHEMBL4750881) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(F)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)N1CCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.330	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542626 (CHEMBL4637901) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Br)ccc12 Show InChI InChI=1S/C22H23BrN4O3S/c1-31(29,30)10-2-9-25-18(12-15-11-16(23)3-6-19(15)25)14-26-21-13-24-8-7-20(21)27(22(26)28)17-4-5-17/h3,6-8,11-13,17H,2,4-5,9-10,14H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.398	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542653 (CHEMBL4634123) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(CC3CC3)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C23H25ClN4O3S/c1-32(30,31)10-2-9-26-19(12-17-11-18(24)5-6-20(17)26)15-28-22-13-25-8-7-21(22)27(23(28)29)14-16-3-4-16/h5-8,11-13,16H,2-4,9-10,14-15H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.398	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554876 (CHEMBL4747540) Show SMILES CN1CCNC(=O)COc2ccc(Cl)cc2C(=O)N2CCCCC2c2cc3nc(cc1n3n2)N1CCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.470	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542661 (CHEMBL4646241) Show SMILES OC(=O)c1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C26H20ClN5O3/c27-19-5-8-22-18(13-19)14-21(30(22)12-2-1-10-28)16-31-24-15-29-11-9-23(24)32(26(31)35)20-6-3-17(4-7-20)25(33)34/h3-9,11,13-15H,1-2,12,16H2,(H,33,34)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542657 (Jnj-53718678 | Rilematovir) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(CC(F)(F)F)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C21H20ClF3N4O3S/c1-33(31,32)8-2-7-27-16(10-14-9-15(22)3-4-17(14)27)12-28-19-11-26-6-5-18(19)29(20(28)30)13-21(23,24)25/h3-6,9-11H,2,7-8,12-13H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542651 (CHEMBL4636246) Show SMILES CC1(CC1)n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCS(C)(=O)=O)c1=O Show InChI InChI=1S/C23H25ClN4O3S/c1-23(7-8-23)28-20-6-9-25-14-21(20)27(22(28)29)15-18-13-16-12-17(24)4-5-19(16)26(18)10-3-11-32(2,30)31/h4-6,9,12-14H,3,7-8,10-11,15H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542646 (CHEMBL4648807) Show SMILES FCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12 Show InChI InChI=1S/C21H22FN5O/c22-7-1-2-10-25-17(11-15-12-23-8-5-18(15)25)14-26-20-13-24-9-6-19(20)27(21(26)28)16-3-4-16/h5-6,8-9,11-13,16H,1-4,7,10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542662 (CHEMBL4639834) Show SMILES Clc1ccc2n(CCCC#N)c(Cn3c4cnccc4n(-c4ccc(cc4)C(=O)NC4CC4)c3=O)cc2c1 Show InChI InChI=1S/C29H25ClN6O2/c30-21-5-10-25-20(15-21)16-24(34(25)14-2-1-12-31)18-35-27-17-32-13-11-26(27)36(29(35)38)23-8-3-19(4-9-23)28(37)33-22-6-7-22/h3-5,8-11,13,15-17,22H,1-2,6-7,14,18H2,(H,33,37)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542666 (CHEMBL4632978) Show SMILES COc1ccc(c(F)c1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O |(9.04,-20.26,;8.01,-21.41,;8.49,-22.87,;10,-23.2,;10.47,-24.66,;9.43,-25.81,;7.93,-25.49,;6.9,-26.63,;7.45,-24.03,;9.91,-27.27,;11.38,-27.74,;12.71,-26.97,;14.04,-27.73,;14.05,-29.28,;12.71,-30.06,;11.37,-29.28,;9.91,-29.76,;9.43,-31.22,;7.92,-31.54,;6.78,-30.5,;5.45,-31.28,;3.99,-30.8,;2.85,-31.83,;1.38,-31.35,;3.17,-33.33,;4.63,-33.8,;5.76,-32.78,;7.3,-32.94,;8.07,-34.28,;9.61,-34.28,;10.38,-35.62,;11.92,-35.62,;13.46,-35.62,;9.01,-28.51,;7.46,-28.51,)| Show InChI InChI=1S/C26H21ClFN5O2/c1-35-20-5-7-23(21(28)14-20)33-24-8-10-30-15-25(24)32(26(33)34)16-19-13-17-12-18(27)4-6-22(17)31(19)11-3-2-9-29/h4-8,10,12-15H,2-3,11,16H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.631	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554877 (CHEMBL4755451) Show SMILES CN1CCNC(=O)COc2ccc(C)cc2C(=O)N2CCCCC2c2cc3nc(cc1n3n2)N1CCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.640	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50541842 (CHEMBL4647328) Show SMILES CC[C@@H]1N(C)C(=O)c2cc(C)ccc2OCCCCN(C)c2cc(nc3cc1nn23)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C27H37N7O2/c1-5-22-21-15-25-29-24(33-12-10-19(28)17-33)16-26(34(25)30-21)31(3)11-6-7-13-36-23-9-8-18(2)14-20(23)27(35)32(22)4/h8-9,14-16,19,22H,5-7,10-13,17,28H2,1-4H3/t19-,22-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.660	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Human respiratory syncytial virus A2 Fusion protein expressed in Hep2 cells assessed as reduction in virus-induced cytopathic effect af...				ACS Med Chem Lett 11: 1145-1151 (2020) Article DOI: 10.1021/acsmedchemlett.0c00008 BindingDB Entry DOI: 10.7270/Q2GB27NK
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554856 (CHEMBL4740044) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(Cl)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)[C@H]1C[C@H](O)C1 |r,wU:34.38,wD:1.0,36.41,(13.73,-43.38,;14.51,-42.05,;15.29,-43.38,;16.82,-43.38,;17.59,-42.04,;16.81,-40.71,;15.27,-40.71,;14.49,-39.38,;12.95,-39.39,;15.26,-38.04,;16.8,-38.04,;17.56,-36.7,;19.1,-36.7,;16.78,-35.37,;15.24,-35.38,;14.48,-36.72,;12.94,-36.73,;11.74,-37.51,;11.5,-35.99,;12.71,-35.03,;10.22,-35.65,;9.47,-37.05,;10.34,-38.05,;9.27,-38.98,;7.94,-38.21,;9.27,-40.52,;7.94,-41.3,;7.94,-42.84,;9.27,-43.6,;10.61,-42.84,;12.08,-43.31,;12.98,-42.06,;12.06,-40.81,;10.6,-41.3,;6.61,-43.61,;6.21,-45.1,;4.73,-44.71,;3.39,-45.48,;5.12,-43.22,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein D486N mutant in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effe...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554874 (CHEMBL4746199) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(F)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)[C@H]1C[C@H](O)C1 |r,wU:34.38,wD:1.0,36.41,(58.55,-22.17,;59.34,-20.84,;60.11,-22.17,;61.64,-22.17,;62.41,-20.83,;61.64,-19.5,;60.09,-19.5,;59.32,-18.17,;57.78,-18.18,;60.08,-16.83,;61.62,-16.83,;62.38,-15.49,;63.92,-15.49,;61.61,-14.16,;60.06,-14.17,;59.3,-15.51,;57.76,-15.52,;56.56,-16.3,;56.33,-14.79,;57.48,-13.76,;55.04,-14.44,;54.3,-15.84,;55.16,-16.84,;54.09,-17.77,;52.76,-17,;54.09,-19.31,;52.76,-20.09,;52.76,-21.63,;54.09,-22.39,;55.43,-21.63,;56.9,-22.1,;57.8,-20.85,;56.89,-19.61,;55.42,-20.09,;51.43,-22.41,;51.04,-23.89,;49.55,-23.5,;48.22,-24.27,;49.95,-22.01,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.740	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554875 (CHEMBL4765002) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(C)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)[C@H]1C[C@H](O)C1 |r,wU:34.38,wD:1.0,36.41,(80.59,-8.73,;81.38,-7.41,;82.15,-8.74,;83.69,-8.73,;84.46,-7.4,;83.68,-6.07,;82.14,-6.07,;81.36,-4.74,;79.82,-4.75,;82.12,-3.4,;83.66,-3.4,;84.43,-2.06,;85.97,-2.06,;83.65,-.73,;82.1,-.74,;81.35,-2.08,;79.81,-2.09,;78.6,-2.87,;78.37,-1.35,;79.52,-.33,;77.09,-1,;76.34,-2.4,;77.2,-3.4,;76.14,-4.34,;74.8,-3.57,;76.14,-5.88,;74.81,-6.66,;74.81,-8.2,;76.14,-8.96,;77.47,-8.2,;78.94,-8.67,;79.84,-7.42,;78.93,-6.17,;77.46,-6.66,;73.48,-8.97,;73.08,-10.46,;71.59,-10.06,;70.26,-10.84,;71.99,-8.58,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.770	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542632 (CHEMBL4640078) Show SMILES FCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C22H22ClFN4O/c23-16-3-6-19-15(11-16)12-18(26(19)10-2-1-8-24)14-27-21-13-25-9-7-20(21)28(22(27)29)17-4-5-17/h3,6-7,9,11-13,17H,1-2,4-5,8,10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.794	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50286846 (CHEMBL4169507) Show SMILES CC(C)OC(=O)N1CC2(C1)C(=O)N(Cc1nc3cc(Br)ccc3n1CCCCO)c1ccccc21 Show InChI InChI=1S/C26H29BrN4O4/c1-17(2)35-25(34)29-15-26(16-29)19-7-3-4-8-21(19)31(24(26)33)14-23-28-20-13-18(27)9-10-22(20)30(23)11-5-6-12-32/h3-4,7-10,13,17,32H,5-6,11-12,14-16H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
WuXi AppTec (Shanghai) Co., Ltd Curated by ChEMBL					Assay Description Inhibition of RSV long strain fusion protein infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by CCK8 ass...				ACS Med Chem Lett 9: 94-97 (2018) Article DOI: 10.1021/acsmedchemlett.7b00418 BindingDB Entry DOI: 10.7270/Q23F4S6R
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554864 (CHEMBL4747375) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(F)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)N1CC(O)C1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.810	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554859 (CHEMBL4747256) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(F)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)[C@@H]1C[C@H](N)C1 |r,wU:34.38,36.41,wD:1.0,(37.48,-24.69,;38.26,-23.37,;39.04,-24.7,;40.57,-24.69,;41.34,-23.36,;40.57,-22.03,;39.02,-22.03,;38.25,-20.7,;36.71,-20.71,;39.01,-19.36,;40.55,-19.36,;41.31,-18.02,;42.85,-18.02,;40.54,-16.69,;38.99,-16.7,;38.23,-18.04,;36.69,-18.05,;35.49,-18.83,;35.26,-17.31,;36.4,-16.29,;33.97,-16.96,;33.22,-18.36,;34.09,-19.36,;33.02,-20.3,;31.69,-19.53,;33.02,-21.84,;31.69,-22.62,;31.69,-24.16,;33.02,-24.92,;34.36,-24.16,;35.83,-24.63,;36.73,-23.38,;35.82,-22.13,;34.35,-22.62,;30.36,-24.93,;28.87,-24.54,;28.48,-26.02,;27.15,-26.8,;29.97,-26.42,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.870	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542645 (CHEMBL4639912) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12 Show InChI InChI=1S/C21H23N5O3S/c1-30(28,29)10-2-9-24-17(11-15-12-22-7-5-18(15)24)14-25-20-13-23-8-6-19(20)26(21(25)27)16-3-4-16/h5-8,11-13,16H,2-4,9-10,14H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542644 (CHEMBL4633557) Show SMILES CC(C)CCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2nc(Cl)ccc12 Show InChI InChI=1S/C21H23ClN6O/c1-13(2)8-10-26-16-5-6-18(22)24-20(16)25-19(26)12-27-17-11-23-9-7-15(17)28(21(27)29)14-3-4-14/h5-7,9,11,13-14H,3-4,8,10,12H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542643 (CHEMBL4641189) Show SMILES FC(F)(F)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2nc(Cl)ccc12 Show InChI InChI=1S/C20H18ClF3N6O/c21-16-5-4-14-18(26-16)27-17(28(14)9-1-7-20(22,23)24)11-29-15-10-25-8-6-13(15)30(19(29)31)12-2-3-12/h4-6,8,10,12H,1-3,7,9,11H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50450572 (CHEMBL4164975) Show SMILES Cc1ccc2nc(cc(NCCCN)c2c1)N1CCS(=O)(=O)c2ccccc2C1 Show InChI InChI=1S/C22H26N4O2S/c1-16-7-8-19-18(13-16)20(24-10-4-9-23)14-22(25-19)26-11-12-29(27,28)21-6-3-2-5-17(21)15-26/h2-3,5-8,13-14H,4,9-12,15,23H2,1H3,(H,24,25)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of RSV Long fusion protein assessed as protection against virus induced cytopathic effect in infected human Hep2 cells after 5 days by CCK...				J Med Chem 61: 10228-10241 (2018) Article DOI: 10.1021/acs.jmedchem.8b01394 BindingDB Entry DOI: 10.7270/Q2445Q18
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542669 (CHEMBL4646649) Show SMILES COc1ccc(c(C)c1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O |(57.69,-18.88,;56.66,-20.03,;57.13,-21.49,;58.64,-21.82,;59.11,-23.28,;58.08,-24.42,;56.58,-24.11,;55.55,-25.25,;56.1,-22.64,;58.56,-25.88,;60.02,-26.36,;61.35,-25.59,;62.68,-26.35,;62.69,-27.9,;61.35,-28.67,;60.02,-27.9,;58.55,-28.38,;58.07,-29.84,;56.57,-30.16,;55.42,-29.12,;54.09,-29.89,;52.63,-29.42,;51.49,-30.44,;50.03,-29.97,;51.81,-31.95,;53.27,-32.42,;54.41,-31.4,;55.94,-31.56,;56.71,-32.9,;58.25,-32.9,;59.02,-34.23,;60.56,-34.24,;62.1,-34.23,;57.65,-27.13,;56.11,-27.13,)| Show InChI InChI=1S/C27H24ClN5O2/c1-18-13-22(35-2)6-8-23(18)33-25-9-11-30-16-26(25)32(27(33)34)17-21-15-19-14-20(28)5-7-24(19)31(21)12-4-3-10-29/h5-9,11,13-16H,3-4,12,17H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50277049 (CHEMBL4169195) Show SMILES CS(=O)(=O)c1nn(Cc2nc3cc(Cl)ccc3n2CCC(O)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C19H17ClF3N5O3S/c1-32(30,31)18-12-4-6-24-9-15(12)28(26-18)10-17-25-13-8-11(20)2-3-14(13)27(17)7-5-16(29)19(21,22)23/h2-4,6,8-9,16,29H,5,7,10H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of Respiratory syncytial virus Long fusion glycoprotein infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect af...				Eur J Med Chem 138: 1147-1157 (2017) Article DOI: 10.1016/j.ejmech.2017.07.032 BindingDB Entry DOI: 10.7270/Q2V127BV
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554873 (CHEMBL4752524) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(F)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)[C@@H]1C[C@H](O)C1 |r,wU:34.38,36.41,wD:1.0,(57.15,-9.85,;57.93,-8.53,;58.71,-9.86,;60.24,-9.85,;61.01,-8.52,;60.24,-7.19,;58.69,-7.19,;57.92,-5.86,;56.38,-5.87,;58.68,-4.52,;60.22,-4.52,;60.98,-3.18,;62.52,-3.18,;60.21,-1.85,;58.66,-1.86,;57.9,-3.2,;56.36,-3.21,;55.16,-3.99,;54.93,-2.47,;56.08,-1.45,;53.64,-2.12,;52.89,-3.52,;53.76,-4.52,;52.69,-5.46,;51.36,-4.69,;52.69,-7,;51.36,-7.78,;51.36,-9.32,;52.69,-10.08,;54.03,-9.32,;55.5,-9.79,;56.4,-8.54,;55.49,-7.29,;54.02,-7.78,;50.03,-10.09,;48.54,-9.7,;48.15,-11.18,;46.82,-11.96,;49.64,-11.58,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554872 (CHEMBL4751254) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(F)ccc1OCC(=O)NCCN(C)c1cc(nc3cc2nn13)[C@H]1C[C@H](N)C1 |r,wU:34.38,wD:1.0,36.41,(36.63,-39.84,;37.42,-38.51,;38.19,-39.84,;39.73,-39.84,;40.5,-38.5,;39.72,-37.17,;38.18,-37.17,;37.4,-35.84,;35.86,-35.85,;38.16,-34.51,;39.7,-34.5,;40.47,-33.17,;42.01,-33.16,;39.69,-31.83,;38.14,-31.85,;37.39,-33.18,;35.85,-33.2,;34.64,-33.97,;34.41,-32.46,;35.56,-31.43,;33.13,-32.11,;32.38,-33.51,;33.24,-34.51,;32.18,-35.44,;30.84,-34.67,;32.18,-36.98,;30.85,-37.76,;30.85,-39.3,;32.18,-40.06,;33.51,-39.3,;34.98,-39.77,;35.88,-38.52,;34.97,-37.28,;33.51,-37.76,;29.52,-40.08,;29.12,-41.57,;27.63,-41.17,;26.3,-41.94,;28.03,-39.68,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542625 (CHEMBL4642110) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Br)ccc12 Show InChI InChI=1S/C22H23BrN4O2/c23-16-3-6-19-15(11-16)12-18(25(19)9-1-2-10-28)14-26-21-13-24-8-7-20(21)27(22(26)29)17-4-5-17/h3,6-8,11-13,17,28H,1-2,4-5,9-10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542660 (CHEMBL4643568) Show SMILES Cc1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C26H22ClN5O/c1-18-4-7-21(8-5-18)32-24-10-12-29-16-25(24)31(26(32)33)17-22-15-19-14-20(27)6-9-23(19)30(22)13-3-2-11-28/h4-10,12,14-16H,2-3,13,17H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542664 (CHEMBL4641591) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C26H19ClF3N5O2/c27-18-3-8-22-17(13-18)14-20(33(22)12-2-1-10-31)16-34-24-15-32-11-9-23(24)35(25(34)36)19-4-6-21(7-5-19)37-26(28,29)30/h3-9,11,13-15H,1-2,12,16H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554867 (CHEMBL4752460) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(F)ccc1OCC(=O)N(C)CCN(C)c1cc(nc3cc2nn13)N1CCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus A (strain A2))	BDBM50554866 (CHEMBL4753413) Show SMILES [H][C@@]12CCCCN1C(=O)c1cc(F)ccc1OCCNCCN(C)c1cc(nc3cc2nn13)N1CCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of F protein in Respiratory syncytial virus A2 infected in HepG2 cells assessed as reduction in virus-induced cytopathic effect incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115818 BindingDB Entry DOI: 10.7270/Q2FT8QQ2
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50541846 (CHEMBL4632659) Show SMILES CC[C@@H]1N(C)C(=O)c2cc(C)ccc2OCCCCNc2c(C)c(nc3cc1nn23)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C27H37N7O2/c1-5-22-21-15-24-30-26(33-12-10-19(28)16-33)18(3)25(34(24)31-21)29-11-6-7-13-36-23-9-8-17(2)14-20(23)27(35)32(22)4/h8-9,14-15,19,22,29H,5-7,10-13,16,28H2,1-4H3/t19-,22-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Human respiratory syncytial virus A2 Fusion protein expressed in Hep2 cells assessed as reduction in virus-induced cytopathic effect af...				ACS Med Chem Lett 11: 1145-1151 (2020) Article DOI: 10.1021/acsmedchemlett.0c00008 BindingDB Entry DOI: 10.7270/Q2GB27NK
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542656 (CHEMBL4648250) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CN(C3)S(C)(=O)=O)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C23H26ClN5O5S2/c1-35(31,32)9-3-8-27-18(11-16-10-17(24)4-5-20(16)27)15-28-22-12-25-7-6-21(22)29(23(28)30)19-13-26(14-19)36(2,33)34/h4-7,10-12,19H,3,8-9,13-15H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542650 (CHEMBL4649847) Show SMILES CC(C)n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCS(C)(=O)=O)c1=O Show InChI InChI=1S/C22H25ClN4O3S/c1-15(2)27-20-7-8-24-13-21(20)26(22(27)28)14-18-12-16-11-17(23)5-6-19(16)25(18)9-4-10-31(3,29)30/h5-8,11-13,15H,4,9-10,14H2,1-3H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542673 (CHEMBL4634198) Show SMILES Cn1ccc(n1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C23H20ClN7O/c1-28-11-7-22(27-28)31-20-6-9-26-14-21(20)30(23(31)32)15-18-13-16-12-17(24)4-5-19(16)29(18)10-3-2-8-25/h4-7,9,11-14H,2-3,10,15H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542640 (CHEMBL4647299) Show SMILES CC(C)(O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2nc(Cl)ccc12 Show InChI InChI=1S/C22H25ClN6O2/c1-22(2,31)9-3-11-27-16-6-7-18(23)25-20(16)26-19(27)13-28-17-12-24-10-8-15(17)29(21(28)30)14-4-5-14/h6-8,10,12,14,31H,3-5,9,11,13H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair

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